Antileishmanial Constituents of the Panamanian Endophytic Fungus Edenia sp.

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Antileishmanial constituents of the Panamanian endophytic fungus Edenia sp.

Bioassay-directed fractionation of extracts from the fermentation broth and mycelium of the fungus Edenia sp. led tothe isolation of five antileishmanial compounds, preussomerin EG1 (1), palmarumycin CP2 (2), palmarumycin CP17 (3), palmarumycin CP18 (4), and CJ-12,371 (5). Compounds 3 and 4 are new natural products, and this is only the second report of compound 1. The structures of compounds 1...

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ژورنال

عنوان ژورنال: Journal of Natural Products

سال: 2008

ISSN: 0163-3864,1520-6025

DOI: 10.1021/np800472q